Term Name: | pyrimidine-specific mismatch base pair DNA N-glycosylase activity |
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Synonyms: | G/T-mismatch-specific thymine-DNA glycosylase activity |
Definition: | Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site. |
Ontology: | GO: Molecular Function [GO:0008263] QuickGO AmiGO |