Term Name: complement activation
Synonyms: complement activity, complement cascade, complement response
Definition: Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
Ontology: GO: Biological Process [GO:0006956]    QuickGO    AmiGO

Relationships
is a type of: activation of immune response humoral immune response immune effector process
has subtype: activation of membrane attack complex complement activation, alternative pathway complement activation, classical pathway complement activation, lectin pathway
has_part: protein activation cascade
inverse has_part: complement-dependent cytotoxicity
negatively regulated by: negative regulation of complement activation
positively regulated by: positive regulation of complement activation
regulated by: regulation of complement activation