Term Name: | creatine biosynthetic process |
---|---|
Synonyms: | creatine anabolism, creatine biosynthesis, creatine formation, creatine synthesis |
Definition: | The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle. |
Ontology: | GO: Biological Process [GO:0006601] QuickGO AmiGO |