Term Name: translational initiation
Synonyms: biopolymerisation, biopolymerization, protein synthesis initiation, translation initiation
Definition: The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
Ontology: GO: Biological Process [GO:0006413]    QuickGO    AmiGO

Relationships
is part of: translation
has parts: formation of translation initiation ternary complex methionyl-tRNA formyltransferase activity translation initiation factor activity
is a type of: metabolic process
has subtype: cytoplasmic translational initiation mitochondrial translational initiation
has_part: formation of translation initiation ternary complex
inverse has_part: translation
negatively regulated by: negative regulation of translation in response to oxidative stress negative regulation of translation initiation in response to endoplasmic reticulum stress negative regulation of translational initiation negative regulation of translational initiation in response to osmotic stress negative regulation of translational initiation in response to starvation negative regulation of translational initiation in response to stress
positively regulated by: positive regulation of translation initiation in response to endoplasmic reticulum stress positive regulation of translational initiation positive regulation of translational initiation in response to osmotic stress positive regulation of translational initiation in response to starvation positive regulation of translational initiation in response to stress
regulated by: regulation of translation initiation in response to endoplasmic reticulum stress regulation of translational initiation regulation of translational initiation in response to osmotic stress regulation of translational initiation in response to starvation regulation of translational initiation in response to stress