Term Name: MAP kinase activity
Synonyms: ATP:protein phosphotransferase (MAPKK-activated) activity, ERK, ERK1, ERK2, extracellular signal-regulated kinase activity, MAP kinase 1 activity, MAP kinase 2 activity, MAPK, MBP kinase I activity, MBP kinase II activity, mitogen activated kinase activity, mitogen-activated protein kinase activity, myelin basic protein kinase activity, SAP kinase activity, SAPK, stress-activated kinase activity, stress-activated protein kinase activity
Definition: Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.
Ontology: GO: Molecular Function [GO:0004707]    QuickGO    AmiGO

Relationships
is part of: MAPK cascade
is a type of: protein serine/threonine kinase activity
has subtype: JUN kinase activity
negatively regulated by: negative regulation of MAP kinase activity
positively regulated by: positive regulation of MAP kinase activity
regulated by: regulation of MAP kinase activity