Term Name: | methylenetetrahydrofolate reductase (NAD(P)H) activity |
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Synonyms: | 5,10-CH(2)-H(4)folate reductase activity, 5,10-CH2-H4folate reductase activity, 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity, 5,10-methylenetetrahydrofolate reductase (FADH) activity, 5,10-methylenetetrahydrofolate reductase (FADH2) activity, 5,10-methylenetetrahydrofolate reductase (NADPH) activity, 5,10-methylenetetrahydrofolate reductase activity, 5,10-methylenetetrahydrofolic acid reductase activity, 5,10-methylenetetrahydropteroylglutamate reductase activity, 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity, 5-methyltetrahydrofolate:NAD oxidoreductase activity, 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity, 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity, 5-methyltetrahydrofolate:NAD+ oxidoreductase activity, 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity, 5-methyltetrahydrofolate:NADP+ oxidoreductase activity, MetF, methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity, methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity, methylenetetrahydrofolate reductase (NADPH(2)) activity, methylenetetrahydrofolate reductase (NADPH2), methylenetetrahydrofolate reductase [NAD(P)H], methylenetetrahydrofolate reductase activity, methylenetetrahydrofolic acid reductase activity, MTHFR activity, N(5),N(10)-methylenetetrahydrofolate reductase activity, N(5,10)-methylenetetrahydrofolate reductase activity, N5,10-methylenetetrahydrofolate reductase activity, N5,N10-methylenetetrahydrofolate reductase activity |
Definition: | Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+. |
Ontology: | GO: Molecular Function [GO:0004489] QuickGO AmiGO |