Term Name: | phosphatidylinositol phospholipase C activity |
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Synonyms: | 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity, 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity, monophosphatidylinositol phosphodiesterase activity, phosphatidylinositol-4,5-bisphosphate hydrolysis, phosphoinositidase C activity, phosphoinositide phospholipase C activity, PI-PLC activity, triphosphoinositide phosphodiesterase activity |
Definition: | Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H+. |
Ontology: | GO: Molecular Function [GO:0004435] QuickGO AmiGO |