Term Name: | antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway |
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Synonyms: | endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway |
Definition: | The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family. |
Ontology: | GO: Biological Process [GO:0002488] QuickGO AmiGO |