Term Name: | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent |
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Synonyms: | endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-independent, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent endogenous peptide antigen processing and presentation via MHC class I via ER pathway |
Definition: | The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to classical class I molecules. |
Ontology: | GO: Biological Process [GO:0002486] QuickGO AmiGO |