Term Name: granuloma formation
Synonyms:
Definition: The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic.
Ontology: GO: Biological Process [GO:0002432]    QuickGO    AmiGO

Relationships
is part of: chronic inflammatory response
is a type of: immune effector process
inverse participates_in: multinucleated giant cell
negatively regulated by: negative regulation of granuloma formation
positively regulated by: positive regulation of granuloma formation
regulated by: regulation of granuloma formation