Term Name: | T-helper 1 cell lineage commitment |
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Synonyms: | T-helper 1 cell fate commitment, Th1 cell lineage commitment, Th1 fate commitment |
Definition: | The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis. |
Ontology: | GO: Biological Process [GO:0002296] QuickGO AmiGO |