Term Name: | B-1 B cell homeostasis |
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Synonyms: | B-1 B lymphocyte homeostasis, B-1 B-cell homeostasis, B-1 B-lymphocyte homeostasis |
Definition: | The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity. |
Ontology: | GO: Biological Process [GO:0001922] QuickGO AmiGO |