Term Name: nuclear exosome (RNase complex)
Synonyms: eukaryotic exosome multienzyme ribonuclease complex, nuclear exosome (ribonuclease complex), nuclear exosome multienzyme ribonuclease complex
Definition: A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.
Ontology: GO: Cellular Component [GO:0000176]    QuickGO    AmiGO

Relationships
is part of: nuclear lumen nucleus
is a type of: exosome (RNase complex) nuclear protein-containing complex
has subtype: nucleolar exosome (RNase complex)
inverse has_part: nuclear exosome focus