Term Name: | G2/M transition of mitotic cell cycle |
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Synonyms: | mitotic G2/M transition |
Definition: | The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex. |
Ontology: | GO: Biological Process [GO:0000086] QuickGO AmiGO |