Term Name:	progressive multifocal leukoencephalopathy
Synonyms:	PML
Definition:	A viral infectious disease that involves reactivation of JC polyomavirus in immune-compromised individuals which causes the loss of white matter (which is made up of myelin, a substance the surrounds and protects nerve fibers) in multiple areas of the brain. The symptoms include hemiparesis, aphasia, dysarthria, hemianopia, cognitive impairment and coma.
Ontology:	Human Disease [DOID:643]   ( DOID:643 )