Term Name: | Lynch syndrome |
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Synonyms: | Hereditary Defective Mismatch Repair syndrome, Hereditary non-polyposis colon cancer, Hereditary non-polyposis colon cancer syndrome, Hereditary non-polyposis colorectal cancer, Hereditary non-polyposis colorectal cancer syndrome, Hereditary nonpolyposis colon cancer, Hereditary nonpolyposis colon cancer syndrome, hereditary nonpolyposis colorectal cancer, Hereditary nonpolyposis colorectal cancer syndrome, hereditary nonpolyposis colorectal neoplasm, HNPCC |
Definition: | A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers. |
Ontology: | Human Disease [DOID:3883] ( DOID:3883 ) |