Term Name: | CADASIL 2 |
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Synonyms: | autosomal dominant cerebral arteriopathy with subcortical infarcts and leukoencephalopathy type 2 |
Definition: | A CADASIL characterized by stroke, transient ischemic attacks, cognitive impairment, dementia, balance impairment, gait disturbance, headaches, and/or seizures associated with early confluent or confluent diffuse white matter hyperintensities that has_material_basis_in heterozygous mutation in the HTRA1 gene on chromosome 10q26. |
Ontology: | Human Disease [DOID:0111036] ( DOID:0111036 ) |