Term Name: | leukocyte adhesion deficiency 3 |
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Synonyms: | IADD, integrin activation deficiency disease, LAD1 variant, LAD1V, LAD3, leukocyte adhesion deficiency 1 variant, leukocyte adhesion deficiency type III |
Definition: | A leukocyte adhesion deficiency that is characterized by a defect in beta integrins 1, 2, and 3; which impairs the integrin activation cascade and has_material_basis_in mutation in FERMT3 gene on chromosome 11q12. |
Ontology: | Human Disease [DOID:0110912] ( DOID:0110912 ) |