Term Name: | T2-low asthma |
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Synonyms: | type 2 low endotype |
Definition: | A chronic asthma that is characterized by the pathophysiology phenotype combination (endotype) of non-atopic, smoking, obesity related, and elderly and that is characterized by neutrophilic (sputum neutrophils > 40–60%) or paucigranulocytic (i.e., normal sputum levels of both eosinophils and neutrophils) inflammation and a lack of response to corticosteroid therapy. |
Ontology: | Human Disease [DOID:0080818] ( DOID:0080818 ) |