Term Name: | glucocorticoid-induced osteoporosis |
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Synonyms: | steroid-induced osteoporosis |
Definition: | An osteoporosis caused by chronic glucocorticoid use. Glucocorticoids impair the replication, differentiation and function of osteoblasts and induce the apoptosis of mature osteoblasts and osteocytes; the also favor osteoclastogenesis leading to an increase in bone resorption. |
Ontology: | Human Disease [DOID:0060343] ( DOID:0060343 ) |