Term Name: | rheumatic heart disease |
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Synonyms: | rheumatic carditis |
Definition: | A heart valve disease that is characterized by repeated inflammation with fibrinous repair caused by an autoimmune reaction to Group A beta-hemolytic streptococci (GAS) that results in valvular damage. The cardinal anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords. |
Ontology: | Human Disease [DOID:0050827] ( DOID:0050827 ) |