Term Name: interstitial cell of Cajal
Synonyms: ICC, intestinal pacemaker cell
Definition: This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise.
Ontology: Cell Ontology [CL:0002088]

Relationships
is a type of: neurecto-epithelial cell
capable_of: regulation of hindgut contraction