Term Name: | T3 B cell |
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Synonyms: | An1 B cell, T3 B lymphocyte, T3 B-cell, T3 B-lymphocyte, transitional stage 3 B cell |
Definition: | A transitional stage B cell that expresses surface IgM and IgD, and CD62L. This cell type appears to be an anergic B cell that does not proliferate upon BCR signaling, is found in the spleen and lymph nodes, and has the phenotype surface IgM-positive, surface IgD-positive, CD21-positive, CD23-positive, CD62L-positive, and CD93-positive. This cell type has also been described as IgM-low, CD19-positive, B220-positive, AA4-positive, and CD23-positive (i.e. this cell-type is distinguished from T2 cells by surface expression of IgM). |
Ontology: | Cell Ontology [CL:0000960] |