Term Name: | marginal zone B cell |
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Synonyms: | marginal zone B lymphocyte, marginal zone B-cell, marginal zone B-lymphocyte, MZ B cell, MZ B lymphocyte, MZ B-cell, MZ B-lymphocyte |
Definition: | A mature B cell that is located in the marginal zone of the spleen with the phenotype CD23-negative and CD21-positive and expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL. This cell type is also described as being CD19-positive, B220-positive, IgM-high, AA4-negative, CD35-high. |
Ontology: | Cell Ontology [CL:0000845] |