Term Name: | pracinostat |
---|---|
Synonyms: | (2E)-3-{2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl}-N-hydroxyacrylamide, pracinostat, pracinostatum, SB 939, SB-939, SB939 |
Definition: | A hydroxamic acid that is N-hydroxyacrylamide which is substituted at position 3 by a 2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl group (the E isomer). An orally available pan-histone deacetylase inhibitor with demonstrated activity in the treatment of advanced solid tumours. |
Ontology: | ChEBI [CHEBI:95071] ( EBI ) |