Term Name: | cobimetinib fumarate |
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Synonyms: | bis[(2S)-2-{1-[3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoyl]-3-hydroxyazetidin-3-yl}piperidin-1-ium] (2E)-but-2-enedioate, cobimetinib, Cobimetinib hemifumarate, COTELLIC, GDC-0973 hemifumarate, Xl-518 hemifumarate |
Definition: | A fumarate salt prepared from cobimetinib by reaction of one molecule of fumaric acid for every two molecules of cobimetinib. An inhibitor of mitogen-activated protein kinase that is used in combination with vemurafenib for the treatment of patients with unresectable or metastatic melanoma. |
Ontology: | ChEBI [CHEBI:90853] ( EBI ) |