Term Name: BMS-453
Synonyms: 4-[(E)-2-(5,5-dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)vinyl]benzoic acid, BMS 189453, BMS 453, BMS-189453, BMS189453, BMS453
Definition: A member of the class of dihydronaphthalenes that is 1,2-dihydronaphthalene which is substituted at positions 1, 1, 4, and 6 by methyl, methyl, phenyl, and 2-(p-carboxyphenyl)vinyl groups, respectively (the E isomer). It is a potent retinoic acid receptor gamma (RARbeta) agonist that acts as an antagonist against RARalpha and RARgamma.
Ontology: ChEBI [CHEBI:90739]  ( EBI )

Relationships
is a type of: benzoic acids dihydronaphthalenes stilbenoid
has_role: retinoic acid receptor alpha antagonist retinoic acid receptor beta agonist retinoic acid receptor gamma antagonist teratogenic agent