Term Name: | BMS-453 |
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Synonyms: | 4-[(E)-2-(5,5-dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)vinyl]benzoic acid, BMS 189453, BMS 453, BMS-189453, BMS189453, BMS453 |
Definition: | A member of the class of dihydronaphthalenes that is 1,2-dihydronaphthalene which is substituted at positions 1, 1, 4, and 6 by methyl, methyl, phenyl, and 2-(p-carboxyphenyl)vinyl groups, respectively (the E isomer). It is a potent retinoic acid receptor gamma (RARbeta) agonist that acts as an antagonist against RARalpha and RARgamma. |
Ontology: | ChEBI [CHEBI:90739] ( EBI ) |