Term Name: talmapimod
Synonyms: 2-(6-chloro-5-{(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazine-1-carbonyl}-1-methyl-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide, SCIO 469, SCIO-469, SCIO469, Scios 469, talmapimod
Definition: An indolecarboxamide obtained by formal condensation of the carboxy group of 6-chloro-3-[(dimethylamino)(oxo)acetyl]-1-methylindole-5-carboxylic acid with the secondary amino group of (2S,5R)-1-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazine. It is a potent inhibitor of MAPK and exhibits anti-cancer properties.
Ontology: ChEBI [CHEBI:90683]  ( EBI )

Relationships
is a type of: aromatic amide aromatic ketone chloroindole dicarboxylic acid diamide indolecarboxamide monofluorobenzenes N-acylpiperazine N-alkylpiperazine
has_role: antineoplastic agent apoptosis inducer EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor