Term Name: | tacedinaline |
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Synonyms: | 4-(Acetylamino)-N-(2-aminophenyl)benzamide, 4-acetamido-N-(2-aminophenyl)benzamide, Acetyldinaline, C.I. 994, CI 994, CI-994, N-acetyldinaline, tacedinalina, tacedinaline |
Definition: | A benzamide obtained by formal condensation of the carboxy group of 4-acetamidobenzoic acid with one of the amino groups of 1,2-phenylenediamine. An oral cytostatic drug with impressive differential activity against leukemic cells and normal stem-cells. Also used in combination therapy for selected tumors including non-smoll cell lung, pancreatic, breast, and colorectal cancers. |
Ontology: | ChEBI [CHEBI:90195] ( EBI ) |