Term Name: mycophenolate mofetil
Synonyms: 2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate, 2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate, Cellcept, MMF, mycophenolic acid morpholinoethyl ester, RS 61443
Definition: A carboxylic ester resulting from the formal condensation between the carboxylic acid group of mycophenolic acid and the hydroxy group of 2-(morpholin-4-yl)ethanol. In the liver, it is metabolised to mycophenolic acid, an immunosuppressant for which it is a prodrug. It is widely used to prevent tissue rejection following organ transplants as well as for the treatment of certain autoimmune diseases.
Ontology: ChEBI [CHEBI:8764]  ( EBI )

Relationships
is a type of: carboxylic ester ether gamma-lactone phenols tertiary amino compound
has_functional_parent: 2-(morpholin-4-yl)ethanol mycophenolic acid
has_role: anticoronaviral agent EC 1.1.1.205 (IMP dehydrogenase) inhibitor immunosuppressive agent prodrug