Term Name: | conazole antifungal agent |
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Synonyms: | azole antibiotic, azole antibiotics, conazole antifungal agents |
Definition: | A compound that has a structure that is related to miconazole, contains an azole (imidazole or triazole) moiety, and has significant systemic antifungal properties. They inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. |
Ontology: | ChEBI [CHEBI:86323] ( EBI ) |