Term Name: panobinostat
Synonyms: (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enamide, LBH 589, LBH589, panobinostat
Definition: A hydroxamic acid obtained by formal condensation of the carboxy group of (2E)-3-[4-({[2-(2-methylindol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enoic acid with the amino group of hydroxylamine. A histone deacetylase inhibitor used (as its lactate salt) in combination with bortezomib and dexamethasone for the treatment of multiple myeloma.
Ontology: ChEBI [CHEBI:85990]  ( EBI )

Relationships
is a type of: cinnamamides hydroxamic acid methylindole secondary amino compound
has_role: angiogenesis modulating agent antineoplastic agent EC 3.5.1.98 (histone deacetylase) inhibitor
inverse is_conjugate_acid_of: panobinostat(1+)
is_conjugate_base_of: panobinostat(1+)