Term Name: | 5'-ATGGACCAAAGAGTTTCAGGGA-3' |
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Synonyms: | 5'-ApTpGpGpApCpCpApApApGpApGpTpTpTpCpApGpGpGpA-3', 5'-d[ATGGACCAAAGAGTTTCAGGGA]-3', d(A-T-G-G-A-C-C-A-A-A-G-A-G-T-T-T-C-A-G-G-G-A), d(ATGGACCAAAGAGTTTCAGGGA), HPS |
Definition: | A single-stranded DNA oligonucleotide comprised of eight deoxyadenosine, four thymidine, three deoxycytidine and seven deoxyguanosine residues connected by 3'->5' phosphodiester linkages in the sequence ATGGACCAAAGAGTTTCAGGGA. It is a mimic of HuR mRNA nucleotides 671-692 and acts as an antagonist that deregulates human antigen R (HuR) expression and inhibits AKT(SER473) phosphorylation in prostate and other cancers. |
Ontology: | ChEBI [CHEBI:85516] ( EBI ) |