Term Name: syrbactin
Synonyms: syrbactins
Definition: A class of azamacrocyclic natural products with a 2,7-dioxo-1,6-diazacyclododecane skeleton that includes the syringolin, glidobactin and cepafungin natural product families. In addition to their related molecular frameworks, members of the class share similar biosynthesis pathways and identical modes-of-action, being irreversible proteasome inhibitor that inhibit all three activities of eukaryotic proteasomes.
Ontology: ChEBI [CHEBI:82671]  ( EBI )

Relationships
is a type of: azamacrocycle lactam
has subtype: syringolin A
has_role: metabolite proteasome inhibitor
inverse has_functional_parent: luminmycin A