Term Name: | phosphorothioate oligonucleotide |
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Synonyms: | oligo(nucleoside phosphorothioate), oligo(nucleoside phosphorothioate)s, oligonucleotide phosphorothioate, oligonucleotide phosphorothioates, OPS, phosphorothioate DNA, phosphorothioate oligonucleotides, PS DNA, PS-DNA, S-oligo, S-oligos |
Definition: | An oligonucleotide in which one of the non-bridging oxygens in each phosphodiester linkage has been replaced by sulfur. The main application of phosphorothioate linkages in an oligonucleotide is to protect the oligonucleotide from nuclease degradation. |
Ontology: | ChEBI [CHEBI:76674] ( EBI ) |