Term Name: | (S)-ketorolac |
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Synonyms: | (-)-ketorolac, (1S)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, (S)-(-)-ketorolac |
Definition: | A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has S configuration. While (S)-ketorolac is a COX1 and COX2 inhibitor, both enantiomers exhibit analgesic effects. Racemic ketorolac, known simply as ketorolac, is used (mainly as the tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. |
Ontology: | ChEBI [CHEBI:76228] ( EBI ) |