Term Name: | (R)-ketorolac |
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Synonyms: | (+)-ketorolac, (1R)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, (R)-(+)-ketorolac |
Definition: | A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has R configuration. Unlike the S-enantiomer, it does not exhibit COX1 and COX2 inhibition, but does exhibit analgesic activity. Racemic ketorolac, known simply as ketorolac, is used (mainly as a tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. |
Ontology: | ChEBI [CHEBI:76227] ( EBI ) |