Term Name: dolutegravir
Synonyms: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, S/GSK1349572
Definition: A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (4R,12aS)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid with the amino group of 2,4-difluorobenzylamine. Used (as its sodium salt) for treatment of HIV-1.
Ontology: ChEBI [CHEBI:76010]  ( EBI )

Relationships
is a type of: difluorobenzene monocarboxylic acid amide organic heterotricyclic compound secondary carboxamide
has_role: HIV-1 integrase inhibitor
inverse is_conjugate_base_of: dolutegravir(1-)
is_conjugate_acid_of: dolutegravir(1-)