Term Name: teniposide
Synonyms: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-(thiophen-2-ylmethylidene)-beta-D-glucopyranoside, 4'-Demethylepipodophyllotoxin 9-(4,6-O-2-thenylidene-beta-D-glucopyranoside), 4'-Demethylepipodophyllotoxin-beta-D-thenylidene glucoside, HSDB 6546, NSC 122819, NSC-122819, teniposide, teniposido, teniposidum, VM-26, VM26, Vumon
Definition: A furonaphthodioxole that is a synthetic derivative of podophyllotoxin with anti-tumour activity; causes single- and double-stranded breaks in DNA and DNA-protein cross-links and prevents repair by topoisomerase II binding.
Ontology: ChEBI [CHEBI:75988]  ( EBI )

Relationships
is a type of: aromatic ether beta-D-glucoside cyclic acetal furonaphthodioxole gamma-lactone monosaccharide derivative phenols thiophenes
has_functional_parent: podophyllotoxin
has_role: antineoplastic agent EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor