Term Name: acivicin
Synonyms: (2S)-amino[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]acetic acid, (alpha-S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid, (alphaS,5S)-alpha-amino-3-chloro-2-isoxazoline-5-acetic acid, acivicin, acivicine, acivicino, acivicinum, Antibiotic AT 125, AT 125, AT-125, NSC 163501, NSC-163501, U 42126, U-42,126
Definition: An L-alpha-amino acid that is L-alanine in which the methyl group is replaced by a (5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl group. A glutamine analogue antimetabolite, it interferes with glutamate metabolism and several glutamate-dependent synthetic enzymes. It is obtained as a fermentation product of Streptomyces sviceus bacteria.
Ontology: ChEBI [CHEBI:74545]  ( EBI )

Relationships
is a type of: isoxazoles non-proteinogenic L-alpha-amino acid organochlorine compound
has_role: antileishmanial agent antimetabolite antimicrobial agent antineoplastic agent EC 2.3.2.2 (gamma-glutamyltransferase) inhibitor glutamine antagonist metabolite