Term Name: | acivicin |
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Synonyms: | (2S)-amino[(5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl]acetic acid, (alpha-S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid, (alphaS,5S)-alpha-amino-3-chloro-2-isoxazoline-5-acetic acid, acivicin, acivicine, acivicino, acivicinum, Antibiotic AT 125, AT 125, AT-125, NSC 163501, NSC-163501, U 42126, U-42,126 |
Definition: | An L-alpha-amino acid that is L-alanine in which the methyl group is replaced by a (5S)-3-chloro-4,5-dihydro-1,2-oxazol-5-yl group. A glutamine analogue antimetabolite, it interferes with glutamate metabolism and several glutamate-dependent synthetic enzymes. It is obtained as a fermentation product of Streptomyces sviceus bacteria. |
Ontology: | ChEBI [CHEBI:74545] ( EBI ) |