Term Name: bedaquiline
Synonyms: (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(1-naphthyl)-1-phenylbutan-2-ol, 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-ol, bedaquilina, bedaquiline, bedaquilinum, R 207910, R207910, TMC 207, TMC-207, TMC207
Definition: A quinoline-based antimycobacterial drug used (as its fumarate salt) for the treatment of pulmonary multi-drug resistant tuberculosis by inhibition of ATP synthase, an enzyme essential for the replication of the mycobacteria.
Ontology: ChEBI [CHEBI:72292]  ( EBI )

Relationships
is a type of: aromatic ether naphthalenes organobromine compound quinolines tertiary alcohol tertiary amino compound
has_role: antitubercular agent ATP synthase inhibitor
inverse is_conjugate_acid_of: bedaquiline(2+)
is_conjugate_base_of: bedaquiline(2+)