Term Name: withaferin A
Synonyms: (4beta,5beta,6beta,22R)-4,27-dihydroxy-5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione, 4beta,27-dihydroxy-1-oxo-5beta,6beta-epoxywitha-2,24-dienolide, Withaferin A
Definition: A withanolide that is 5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione substituted by hydroxy groups at positions 4 and 27 (the 4beta,5beta,6beta,22R stereoisomer). Isolated from Physalis longifolia, it exhibits cytotoxic activity.
Ontology: ChEBI [CHEBI:69120]  ( EBI )

Relationships
is a type of: 4-hydroxy steroid 27-hydroxy steroid delta-lactone enone epoxy steroid ergostanoid primary alcohol secondary alcohol withanolide
has_role: antineoplastic agent apoptosis inducer
inverse has_functional_parent: 2,3-dihydro-3beta-methoxy withaferin A 2,3-dihydro-3beta-O-sulfate withaferin A 2,3-dihydrowithaferin A sitoindoside IX withalongolide A withalongolide B withalongolide C withalongolide G withalongolide H