Term Name: apoptosis inducer
Synonyms: apoptosis inducers, Type I cell-death inducer, Type I cell-death inducers, Type I programmed cell-death inducer, Type I programmed cell-death inducers
Definition: Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
Ontology: ChEBI [CHEBI:68495]  ( EBI )

Relationships
is a type of: biochemical role
has subtype: survivin suppressant
inverse has_role: (-)-coronaridine (-)-epigallocatechin 3-gallate (-)-noscapine (2E)-2-benzylidene-3-(cyclohexylamino)indan-1-one (2E,4E)-deca-2,4-dienal (9E,11E)-octadecadienoic acid (20S)-ginsenoside Rg3 (20S)-ginsenoside Rh2 (25R)-cholest-5-ene-3beta,26-diol (E)-2-[[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene]methyl]benzoic acid (E)-3-tosylacrylonitrile (E)-trans-miyabenol C (E,E)-germacrone (R)-amygdalin 1,3,6,8-tetraazatricyclo[6.2.1.1(3,6)]dodecane 1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine 1-stearoyl-sn-glycero-3-phosphocholine 2'-hydroxybiochanin A 2,4-dihydroxy-6-methylbenzaldehyde 2-acetamidophenol 2-amino-3-cyano-7-(dimethylamino)-4-(2-methoxyphenyl)-4H-chromene 2-amino-4-(3-nitrophenyl)-3-cyano-7-(dimethylamino)-4H-chromene 2-hydroxymelatonin 2-hydroxyoleic acid 3,3',5,5'-tetraiodothyroacetic acid 3,3'-dimethylquercetin 3,4'-dimethylkaempferol 3PO 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide 4-hydroxy-TEMPO 4-hydroxycinnamaldehyde 4-iodo-6-phenylpyrimidine 4-methoxy-TEMPO 4-phenylbutyric acid 4-terpineol 5-(N,N-hexamethylene)amiloride 5-(tetradecyloxy)-2-furoic acid 6-diazo-5-oxo-L-norleucine 18-hydroxyoctadecanoic acid 10058-F4 abexinostat ABT-737 acalabrutinib aclacinomycin A aclacinomycin A zwitterion actinodaphnine AEE788 akebia saponin D alantolactone alisertib allyl isothiocyanate alpha-tocopheryloxyacetic acid alsterpaullone alvocidib alvocidib hydrochloride AM-251 AMG-925 amrubicinol anacardic acid antimony trichloride AOH1996 aphidicolin AR-42 AS1842856 ASP-3026 atromentin auraptene avenanthramide B AZD-8055 AZD1080 AZD3463 AZD7762 b-AP15 bafilomycin A1 baicalein BAR0329 BAY 73-6691 BAY11-7085 BCI-215 BDA-366 beta-tocotrienol BI-2536 bigelovin binimetinib bis(S-citronellalthiosemicarbazonato)nickel(II) bixin bleomycin A5 BMS-214662 borrelidin brazilin brivanib brivanib alaninate C-1027 chromophore C75 C646 cadiyenol cafestol calmidazolium calmidazolium chloride CAN-508 cantharidic acid carminomycin carnosic acid casticin CBL0137 CCT-018159 CD437 CG-1521 CHIR-265 CHIR-98014 chrysazin CIGB-300 cis-9-nonadecenoic acid cisplatin CM-272 columbianadin copanlisib copanlisib dihydrochloride CP-724714 cratoxylumxanthone C crenolanib CX-5461 cytotrienin A DC_517 deguelin dehydrocostus lactone delanzomib delphinidin 3-O-beta-D-sambubioside delta-elemene delta-tocotrienol deoxypodophyllotoxin devazepide diallyl trisulfide dibromoacetic acid diethyl sulfate dinaciclib dioscin diosgenin diosmetin disulfiram DMH4 dolastatin 10 dutomycin ebselen edelfosine elesclomol elesclomol-Cu(II) eltanexor entinostat entrectinib epothilone B ethyl 3,4-dihydroxybenzoate eugenol eupatorin Fasnall flavokawain B fluazinam foretinib fraxetin galactoxylomannan gallic acid gamma-tocotrienol GANT61 GDC-0623 ghrelin GI254023X gilteritinib ginsenoside F2 ginsenoside Rd ginsenoside Rf givinostat givinostat hydrochloride givinostat hydrochloride monohydrate gnidilatimonoein GSK343 GSK461364 guttiferone F GW843682X harmol helveticoside herbacetin herbimycin hexadecan-2-ol hexafluoropropylene oxide trimer acid hispidulin HMN-214 HT-2 toxin hydrogen peroxide hyperforin I-BET151 iberin icariside II ICRF-193 idelalisib ikarugamycin imatinib imatinib methanesulfonate indirubin irinotecan irinotecan hydrochloride (anhydrous) irinotecan hydrochloride hydrate isoalantolactone isorhamnetin 3-O-robinobioside isosilybin A ixazomib ixazomib citrate jaceosidin jadomycin B jaspamide JM335 JQ1 JTE-607 dihydrochloride JTE-607 free base kaempferol 3,7-di-O-alpha-L-rhamnoside kahweol Ki11502 KP1019 KP1339 KRIBB11 KU-55933 laminarin lancovutide lanthanum trichloride laurinterol LB42908 LCL161 LDC4297 LFM-A13 licocoumarone lificiguat linsitinib lobaplatin lupulone luteolin LY-2090314 LY3009120 mancozeb manumycin A mefuparib mefuparib hydrochloride melittin methoxyacetic acid methyl gamma-linolenate methyl isocyanate methyl methanesulfonate methylstat mevastatin MI-63 midazolam midazolam hydrochloride miltefosine mitoguazone mitoguazone hydrochloride mitoguazone hydrochloride hydrate MK-2461 MK-8353 mocetinostat molibresib momelotinib motixafortide motixafortide acetate MP-A08 MST-312 myriocin myristoleic acid N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide N-methyl-4-phenylpyridinium N-methylparoxetine N-nitrosopiperidine N-oleoyltaurine N-succinimidyl N-methylcarbamate naphthazarin natamycin navitoclax neral niclosamide niraparib nitrosulindac nitryl chloride NNC 55-0396 (free base) NNC 55-0396 dihydrochloride nomilin norsalsolinol nortriptyline notoginsenoside R1 NSC 23766 NSC 23766 trihydrochloride olaparib oleocanthal oleuropein omacetaxine mepesuccinate oncrasin-1 ophiobolin C oridonin OSU-03012 PABA/NO pacritinib pannarin PB28 PD-166866 pectolinarin peonidin peonidin chloride pevonedistat PF-3758309 PF-573228 phenylarsine oxide phorbol 13-acetate 12-myristate physalin F physcion piceatannol pimasertib pipercallosidine pipercallosine piperyline pirtobrutinib PJ34 PJ34 hydrochloride plaunotol plinabulin PLS-123 poziotinib pracinostat prodigiosin PS-1145 pterostilbene pyoluteorin resminostat ricolinostat rigosertib rigosertib sodium Ro 41-5253 roducitabine rottlerin rotundifuran rubimaillin S-acetylglutathione salvianolic acid B sapanisertib saracatinib SB 415286 SB-202190 SB225002 SC560 scalaradial SCH-79797 SCH772984 sclareol selinexor sepantronium bromide SKF-96365 hydrochloride SM-164 SMIP004 SN-38 soblidotin sodium gallate sodium methoxyacetate solanine solasodine solasodine(1+) SR9243 staurosporine STM2457 SU11274 sulindac sulindac sulfide sulindac sulfone syringin T-2 toxin tabernaemontanine tabtoxinine beta-lactam tafenoquine TAK-580 TAK-632 TAK-733 talmapimod tanespimycin tasisulam TDZD-8 telatinib tetrazolium violet TG101209 thallium(I) acetate theasinensin A thiostrepton THZ531 tideglusib tilimycin tipifarnib tirapazamine tivozanib toxoflavin toyocamycin trans-rhaponticin triapine tributyrin trichothecin triptohypol C trisodium vanadate TW-37 tyloxapol tyrphostin B42 U0126 U0126.EtOH undecylprodigiosin varlitinib venetoclax violacein vitetrifolin D vitexilactone volasertib vorinostat vosaroxin VX-745 wedelolactone withaferin A xanthohumol XPO1-IN-1 YK-4-279 ziram ZM447439