Term Name: AS-186a
Synonyms: 11-hydroxy-3-[(1S)-1-hydroxy-3-methylbutyl]-4-methoxy-9-methyl-5H,7H-dibenzo[b,g][1,5]dioxocin-5-one, penicillide, vermixocin A
Definition: A dibenzodioxocine that is 5H,7H-dibenzo[b,g][1,5]dioxocin-5-one substituted by a hydroxy group at position 11, a (1S)-1-hydroxy-3-methylbutyl group at position 3 and a methoxy and a methyl group at positions 4 and 9 respectively. It is isolated from the culture broth of Penicillium asperosporum and acts as an acyl-CoA:cholesterol acyltransferase inhibitor.
Ontology: ChEBI [CHEBI:65443]  ( EBI )

Relationships
is a type of: aromatic ether dibenzodioxocine lactone phenols secondary alcohol
has_role: antimicrobial agent EC 2.3.1.26 (sterol O-acyltransferase) inhibitor Penicillium metabolite
inverse has_functional_parent: AS-186b