Term Name: | clobenpropit |
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Synonyms: | 3-(1H-imidazol-4-yl)propyl N-(4-chlorobenzyl)carbamimidothioate, S-(3-(4(5)-Imidazolyl))propyl-N-(4-chlorobenzyl)isothiourea |
Definition: | An imidothiocarbamic ester that consists of isothiourea bearing S-3-(imidazol-4-yl)propyl and N-4-chlorobenzyl substituents. An extremely potent histamine H3 antagonist/inverse agonist (pA2 = 9.93). Also displays partial agonist activity at H4 receptors; induces eosinophil shape change with an EC50 of 3 nM. |
Ontology: | ChEBI [CHEBI:64177] ( EBI ) |