Term Name: 8-bromo-3',5'-cyclic GMP
Synonyms: 8-Br-cGMP, 8-Br-Cyclic GMP, 8-Bromo-cgmp, 8-Bromocyclic GMP, 8-Bromocyclic guanosine monophosphate, 8-bromoguanosine 3',5'-(hydrogen phosphate), 8-Bromoguanosine 3',5'-cyclic monophosphate, 8-Bromoguanosine 3',5'-monophosphate
Definition: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP bearing an additional bromo substituent at position 8 on the guanine ring. A membrane permeable cGMP analogue that activates protein kinase G (PKG). It is 4.3-fold more potent than cGMP in activating PKG1alpha and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro.
Ontology: ChEBI [CHEBI:64108]  ( EBI )

Relationships
is a type of: 3',5'-cyclic purine nucleotide organobromine compound
has_functional_parent: 3',5'-cyclic GMP
has_role: muscle relaxant protein kinase G agonist