Term Name: lamivudine
Synonyms: (-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine, (-)-2'-Deoxy-3'-thiacytidine, 2',3'-Dideoxy-3'-thiacytidine, 3'-Thia-2',3'-dideoxycytidine, 3TC, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one, beta-L-2',3'-Dideoxy-3'-thiacytidine, beta-L-3'-Thia-2',3'-dideoxycytidine, Epivir, Lamivudine
Definition: A monothioacetal that consists of cytosine having a (2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl moiety attached at position 1. An inhibitor of HIV-1 reverse transcriptase, it is used as an antiviral in the treatment of AIDS and hepatitis B.
Ontology: ChEBI [CHEBI:63577]  ( EBI )

Relationships
is a type of: monothioacetal nucleoside analogue oxacycle primary alcohol
has_functional_parent: cytosine
has_role: allergen anti-HBV agent antiviral drug EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor HIV-1 reverse transcriptase inhibitor prodrug