Term Name: | fingolimod |
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Synonyms: | 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol, fingolimod, fingolimodum, FTY720 |
Definition: | An aminodiol that consists of propane-1,3-diol having amino and 2-(4-octylphenyl)ethyl substituents at the 2-position. It is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis. A prodrug, fingolimod is phosphorylated by sphingosine kinase to active metabolite fingolimod-phosphate, a structural analogue of sphingosine 1-phosphate. |
Ontology: | ChEBI [CHEBI:63115] ( EBI ) |