Term Name: | N-Ac-Asp-N(6)-lipoyl-KATIGFEVQEE |
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Synonyms: | lipoated PDC-E2 173-184 peptide, N-Ac-Asp-N(6)-{(R)-lipoyl}-KATIGFEVQEE, N-Ac-Asp-N(6)-{5-[(3R)-1,2-dithiolan-3-yl]pentanoyl}-Lys-Ala-Thr-Ile-Gly-Phe-Glu-Val-Gln-Glu-Glu, N-acetyl-L-alpha-aspartyl-N(6)-{5-[(3R)-1,2-dithiolan-3-yl]pentanoyl}-L-lysyl-L-alanyl-L-threonyl-L-isoleucylglycyl-L-phenylalanyl-L-alpha-glutamyl-L-valyl-L-glutaminyl-L-alpha-glutamyl-L-glutamic acid |
Definition: | A polypeptide comprising the 12-amino acid sequence KATIGFEVQEE where the N-terminal lysyl (K) residue has an acetyl group at the Nalpha-position and a lipoyl group on the side-chain. A component of the inner lipoyl domain of the second enzyme of the pyruvate dehydrogenase complex (PDC-E2), to which antibodies are raised in the autoimmune disease primary biliary cirrhosis. |
Ontology: | ChEBI [CHEBI:60738] ( EBI ) |