Term Name: colistimethate
Synonyms:
Definition: A mixture where R = H or Me. Colistin in which each of the primary amino groups is converted to the corresponding aminomethanesulfonic acid. It is prepared from colistin by the action of formaldehyde followed by sodium bisulfite. A polymyxin antibiotic, it is used as its penta-sodium salt in the treatment of severe infections, particularly of multidrug-resistant Gram-negative bacteria such as Pseudomonas aeruginosa and Acinetobacter baumannii.
Ontology: ChEBI [CHEBI:59662]  ( EBI )

Relationships
is a type of: amino sulfonic acid peptide antibiotic polymyxin
has_functional_parent: colistin
has_part: colistimethate A colistimethate B
has_role: prodrug
inverse is_conjugate_base_of: colistimethate(5-)
is_conjugate_acid_of: colistimethate(5-)